Pub. Date : 2022
PMID : 35419070
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, IL-37 pretreatment reduced the expression of proinflammatory cytokines including tumor necrosis factor-alpha, IL-6, IL-17, and nuclear factor-kappaB (NF-kappaB) in APAP-induced mice. | Acetaminophen | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 2 | Furthermore, IL-37 pretreatment reduced the expression of proinflammatory cytokines including tumor necrosis factor-alpha, IL-6, IL-17, and nuclear factor-kappaB (NF-kappaB) in APAP-induced mice. | Acetaminophen | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 3 | Conclusion: These results demonstrate that delivery of IL-37 plasmid can ameliorate APAP-induced liver injury by reducing proinflammatory cytokines production and preventing the activation of the NF-kappaB signaling pathway. | Acetaminophen | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |