Pub. Date : 2022
PMID : 35401924
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | And the NLRP3 inflammasome was increased in LPS-activated BV-2 microglia cells in the microglia-neuron coculture system; pretreatment with PK11195 and Midazolam limited this undesirable situation. | Midazolam | NLR family, pyrin domain containing 3 | Mus musculus |
| 2 | Taken together, TSPO ligands PK11195 and Midazolam showed neuroprotective effects by reducing the inflammatory response of LPS-activated microglia, which may be related to the enhancement of mitophagy and the inhibition of NLRP3 inflammasome. | Midazolam | NLR family, pyrin domain containing 3 | Mus musculus |