Title : CRISPR-Cas9-based genome-wide screening identified novel targets for treating sorafenib-resistant hepatocellular carcinoma: a cross-talk between FGF21 and the NRF2 pathway.

Pub. Date : 2022 Apr 1

PMID : 35380342






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Using CRISPR/CAS9 genome library screening, we evaluated Kelch-like ECH-associated protein 1 (KEAP1) as a key regulator of sorafenib"s susceptibility in HCC. Sorafenib kelch like ECH associated protein 1 Homo sapiens
2 Using CRISPR/CAS9 genome library screening, we evaluated Kelch-like ECH-associated protein 1 (KEAP1) as a key regulator of sorafenib"s susceptibility in HCC. Sorafenib kelch like ECH associated protein 1 Homo sapiens