Title : Up to 8-year follow-up from RESONATE-2: first-line ibrutinib treatment for patients with chronic lymphocytic leukemia.

Pub. Date : 2022 Jun 14

PMID : 35377947






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1 Here we report extended long-term follow-up from the RESONATE-2 phase 3 study of the once-daily Bruton"s tyrosine kinase inhibitor ibrutinib, which is the only targeted therapy with significant progression-free survival (PFS) and overall survival (OS) benefit in multiple randomized phase 3 CLL studies. ibrutinib Bruton tyrosine kinase Homo sapiens