Pub. Date : 2022
PMID : 35359829
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-kappaB Pathways: Based on Transcriptomics and Metabolomics. | euscaphic acid | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 2 | In addition, the relevant signaling pathways analysis confirmed that TA inhibited HSCs activation by blocking the PI3K/Akt/mTOR pathway and ameliorated inflammatory injury by inhibiting the NF-kappaB pathway. | euscaphic acid | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 3 | In conclusion, TA significantly alleviates liver fibrosis in vivo by inhibiting the glycerophospholipid metabolism pathway and the PI3K/Akt/mTOR and NF-kappaB signaling pathways. | euscaphic acid | AKT serine/threonine kinase 1 | Rattus norvegicus |