Title : Three Classes of Antioxidant Defense Systems and the Development of Postmenopausal Osteoporosis.

Pub. Date : 2022

PMID : 35309045






3 Functional Relationships(s)
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1 We concluded that glutathione/oxidized glutathione (GSH/GSSG) conversion involved the PI3K/Akt-Nrf2/HO-1 signaling pathway and that the antioxidant enzyme-mediated mitochondrial apoptosis pathway of osteoblasts was necessary for the development of postmenopausal osteoporosis. Glutathione NFE2 like bZIP transcription factor 2 Homo sapiens
2 We concluded that glutathione/oxidized glutathione (GSH/GSSG) conversion involved the PI3K/Akt-Nrf2/HO-1 signaling pathway and that the antioxidant enzyme-mediated mitochondrial apoptosis pathway of osteoblasts was necessary for the development of postmenopausal osteoporosis. Glutathione NFE2 like bZIP transcription factor 2 Homo sapiens
3 We concluded that glutathione/oxidized glutathione (GSH/GSSG) conversion involved the PI3K/Akt-Nrf2/HO-1 signaling pathway and that the antioxidant enzyme-mediated mitochondrial apoptosis pathway of osteoblasts was necessary for the development of postmenopausal osteoporosis. Glutathione NFE2 like bZIP transcription factor 2 Homo sapiens