Title : Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause.

Pub. Date : 2022 Feb

PMID : 35306927






3 Functional Relationships(s)
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1 While classical estrogens (such as estradiol) exert their actions via both activation of nuclear and membrane estrogen receptor alpha (ERalpha), E4 presents a specific profile of ERalpha activation: E4 binds and activates nuclear ERalpha but does not induce the activation of membrane ERalpha signaling pathways in specific tissues. Estradiol estrogen receptor 1 Homo sapiens
2 While classical estrogens (such as estradiol) exert their actions via both activation of nuclear and membrane estrogen receptor alpha (ERalpha), E4 presents a specific profile of ERalpha activation: E4 binds and activates nuclear ERalpha but does not induce the activation of membrane ERalpha signaling pathways in specific tissues. Estradiol estrogen receptor 1 Homo sapiens
3 While classical estrogens (such as estradiol) exert their actions via both activation of nuclear and membrane estrogen receptor alpha (ERalpha), E4 presents a specific profile of ERalpha activation: E4 binds and activates nuclear ERalpha but does not induce the activation of membrane ERalpha signaling pathways in specific tissues. Estradiol estrogen receptor 1 Homo sapiens