Pub. Date : 2022 May
PMID : 35304594
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The hypoxia-inducible factor prolyl hydroxylase inhibitor FG4592 promotes natriuresis through upregulation of COX2 in the renal medulla. | roxadustat | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 2 | In addition, FG4592 upregulated the expression of COX2 in the renal medulla. | roxadustat | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 3 | In addition, the COX2 inhibitor celecoxib diminished the natriuretic effect of FG4592. | roxadustat | prostaglandin-endoperoxide synthase 2 | Mus musculus |