Pub. Date : 2022 Jun
PMID : 35277468
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PI(4,5)P2 synthesis is catalyzed by the phosphorylation of phosphatidylinositol 4 phosphate (PI4P) by phosphatidylinositol 4 phosphate 5 kinase (PIP5K). | pi(4,5)p2 | skittles | Drosophila melanogaster |
| 2 | PI(4,5)P2 synthesis is catalyzed by the phosphorylation of phosphatidylinositol 4 phosphate (PI4P) by phosphatidylinositol 4 phosphate 5 kinase (PIP5K). | pi(4,5)p2 | skittles | Drosophila melanogaster |
| 3 | In Drosophila photoreceptors, photon absorption is transduced into PLC activity and during this process, PI(4,5)P2 is resynthesized by a PIP5K. | pi(4,5)p2 | skittles | Drosophila melanogaster |
| 4 | However, the mechanism by which PIP5K activity is coupled to PI(4,5)P2 hydrolysis is unknown. | pi(4,5)p2 | skittles | Drosophila melanogaster |
| 5 | Thus, our work defines a septin-mediated mechanism through which PIP5K activity is coupled to PLC-mediated PI(4,5)P2 hydrolysis. | pi(4,5)p2 | skittles | Drosophila melanogaster |