PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35277468-3	2022	PI(4,5)P2 synthesis is catalyzed by the phosphorylation of phosphatidylinositol 4 phosphate (PI4P) by phosphatidylinositol 4 phosphate 5 kinase (PIP5K).	pi(4,5)p2	0-9	skittles	Drosophila melanogaster	102-143	
35277468-3	2022	PI(4,5)P2 synthesis is catalyzed by the phosphorylation of phosphatidylinositol 4 phosphate (PI4P) by phosphatidylinositol 4 phosphate 5 kinase (PIP5K).	pi(4,5)p2	0-9	skittles	Drosophila melanogaster	145-150	
35277468-4	2022	In Drosophila photoreceptors, photon absorption is transduced into PLC activity and during this process, PI(4,5)P2 is resynthesized by a PIP5K.	pi(4,5)p2	105-114	skittles	Drosophila melanogaster	137-142	
35277468-5	2022	However, the mechanism by which PIP5K activity is coupled to PI(4,5)P2 hydrolysis is unknown.	pi(4,5)p2	61-70	skittles	Drosophila melanogaster	32-37	
35277468-8	2022	Thus, our work defines a septin-mediated mechanism through which PIP5K activity is coupled to PLC-mediated PI(4,5)P2 hydrolysis.	pi(4,5)p2	107-116	skittles	Drosophila melanogaster	65-70