Title : Hematoporphyrin monomethyl ether mediated photodynamic therapy inhibits oral squamous cell carcinoma by regulating the P53-miR-21-PDCD4 axis via singlet oxygen.

Pub. Date : 2022 Mar 9

PMID : 35260928






1 Functional Relationships(s)
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1 1O2 was generated during HMME-PDT, and inhibition of 1O2 production could reverse the regulation of HMME-PDT on P53, miR-21, and its target proteins, thus restoring cell viability. CHEBI:63768 microRNA 21 Homo sapiens