Title : Trimetazidine mitigates high glucose-induced retinal endothelial dysfunction by inhibiting PI3K/Akt/mTOR pathway-mediated autophagy.

Pub. Date : 2022 Mar

PMID : 35259050






1 Functional Relationships(s)
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1 In addition, TMZ intervention increased the expression of p-PI3K, p-AKT, and p-mTOR but decreased the expression of LC3I, LC3II, and Beclin 1, which were then partially reversed by P13 K inhibitor (LY294002). Trimetazidine beclin 1 Homo sapiens