Title : CXCR4 inhibition attenuates calcium oxalate crystal deposition-induced renal fibrosis.

Pub. Date : 2022 Jun

PMID : 35255299






2 Functional Relationships(s)
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1 Mechanistically, activation of the NF-kappaB pathway was suppressed by CXCR4 inhibition in CaOx crystal-induced renal fibrosis; this suppression was significantly aggravated by the NF-kappaB inhibitor BAY-11-7085. BAY 11-7085 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 Mechanistically, activation of the NF-kappaB pathway was suppressed by CXCR4 inhibition in CaOx crystal-induced renal fibrosis; this suppression was significantly aggravated by the NF-kappaB inhibitor BAY-11-7085. BAY 11-7085 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus