Title : Network Pharmacology and Molecular Docking Analysis on Molecular Mechanism of Qingzi Zhitong Decoction in the Treatment of Ulcerative Colitis.

Pub. Date : 2022

PMID : 35237152






3 Functional Relationships(s)
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1 This demonstrated that quercetin, luteolin, hyndarin, and beta-sitosterol had good binding to eight key proteins, and Akt1 was the target protein with the best binding activity, suggesting that Akt1 could be the essential mediator responsible for signaling transduction after QZZTD administration. Quercetin AKT serine/threonine kinase 1 Rattus norvegicus
2 In conclusion, our study suggested four potential key active components, including quercetin, were identified in QZZTD, which could interact with Akt1 and modulate the activation of the PI3K-Akt pathway. Quercetin AKT serine/threonine kinase 1 Rattus norvegicus
3 In conclusion, our study suggested four potential key active components, including quercetin, were identified in QZZTD, which could interact with Akt1 and modulate the activation of the PI3K-Akt pathway. Quercetin AKT serine/threonine kinase 1 Rattus norvegicus