Title : Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer's disease.

Pub. Date : 2022 Mar 2

PMID : 35235058






1 Functional Relationships(s)
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1 A potential candidate for alternative Abeta peptides generation is the metalloproteinase meprin beta, which cleaves APP predominantly at alanine in p2 and in this study we can detect an increased meprin beta expression in AD brain. P-2 meprin 1 beta Mus musculus