Title : The FDA-Approved Drug Cobicistat Synergizes with Remdesivir To Inhibit SARS-CoV-2 Replication In Vitro and Decreases Viral Titers and Disease Progression in Syrian Hamsters.

Pub. Date : 2022 Apr 26

PMID : 35229634






1 Functional Relationships(s)
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1 This was consistent with the effects of cobicistat on two of its known targets, CYP3A4 and P-gp, the silencing of which boosted the in vitro antiviral activity of remdesivir in a cobicistat-like manner. remdesivir cytochrome P450 family 3 subfamily A member 4 Homo sapiens