Title : Metformin reduces chondrocyte pyroptosis in an osteoarthritis mouse model by inhibiting NLRP3 inflammasome activation.

Pub. Date : 2022 Mar

PMID : 35222699






1 Functional Relationships(s)
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1 Regarding the mechanism, in cartilage, metformin increased the expression of Col II and decreased the expression of MMP-13, NLRP3, caspase-1, GSDMD and IL-1beta. Metformin interleukin 1 alpha Mus musculus