Title : Upfront DPYD Genotyping and Toxicity Associated with Fluoropyrimidine-Based Concurrent Chemoradiotherapy for Oropharyngeal Carcinomas: A Work in Progress.

Pub. Date : 2022 Jan 26

PMID : 35200545






2 Functional Relationships(s)
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1 Background: 5-FU-based chemoradiotherapy (CRT) could be associated with severe treatment-related toxicities in patients harboring at-risk DPYD polymorphisms. Fluorouracil dihydropyrimidine dehydrogenase Homo sapiens
2 Upfront DPYD genotyping can identify patients in whom 5-FU-related toxicity should be avoided. Fluorouracil dihydropyrimidine dehydrogenase Homo sapiens