Title : A Critical Period for Development of Cerebellar-Mediated Autism-Relevant Social Behavior.

Pub. Date : 2022 Mar 30

PMID : 35190469






2 Functional Relationships(s)
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1 In this study, we identify a critical period for the development of ASD-relevant behaviors in a cerebellar male mouse model of Tuberous Sclerosis Complex (TSC), by using the mechanistic target of rapamycin (mTOR) inhibitor, rapamycin, to pharmacologically inhibit dysregulated downstream signaling. Sirolimus mechanistic target of rapamycin kinase Mus musculus
2 In this study, we identify a critical period for the development of ASD-relevant behaviors in a cerebellar male mouse model of Tuberous Sclerosis Complex (TSC), by using the mechanistic target of rapamycin (mTOR) inhibitor, rapamycin, to pharmacologically inhibit dysregulated downstream signaling. Sirolimus mechanistic target of rapamycin kinase Mus musculus