Title : Dual action of the cannabinoid receptor 1 ligand arachidonyl-2'-chloroethylamide on calcitonin gene-related peptide release.

Pub. Date : 2022 Feb 21

PMID : 35189809






3 Functional Relationships(s)
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1 Dual action of the cannabinoid receptor 1 ligand arachidonyl-2"-chloroethylamide on calcitonin gene-related peptide release. arachidonyl-2-chloroethylamide cannabinoid receptor 1 Rattus norvegicus
2 The aim of the present study was to examine the effect of the synthetic endocannabinoid (eCB) analogue, arachidonyl-2"-chloroethylamide (ACEA), on calcitonin gene-related peptide (CGRP) release in the dura and trigeminal ganglion (TG), as cannabinoids are known to activate Gi/o-coupled cannabinoid receptors type 1 (CB1), resulting in neuronal inhibition. arachidonyl-2-chloroethylamide cannabinoid receptor 1 Rattus norvegicus
3 The aim of the present study was to examine the effect of the synthetic endocannabinoid (eCB) analogue, arachidonyl-2"-chloroethylamide (ACEA), on calcitonin gene-related peptide (CGRP) release in the dura and trigeminal ganglion (TG), as cannabinoids are known to activate Gi/o-coupled cannabinoid receptors type 1 (CB1), resulting in neuronal inhibition. arachidonyl-2-chloroethylamide cannabinoid receptor 1 Rattus norvegicus