Pub. Date : 2022
PMID : 35185385
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Meanwhile, the increased proteins of NLRP3 and Caspase-1/p20 after LPS instillation in lungs were downregulated by glibenclamide. | Glyburide | caspase 1 | Mus musculus |
2 | In conclusion, glibenclamide alleviates the development of LPS-induced ALI in a mouse model via inhibiting the NLRP3/Caspase-1/IL-1beta signaling pathway, which might provide a new strategy for the treatment of LPS-induced ALI. | Glyburide | caspase 1 | Mus musculus |