Title : Scutellaria brevibracteata Stapf and active principles with anti-inflammatory effects through regulation of NF-κB/COX-2/iNOS pathways.

Pub. Date : 2022 Apr

PMID : 35176423






1 Functional Relationships(s)
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1 3-O-methyl kaempferol, isolated from SB, reduced the production of NO, IL-6 and TNF-alpha in LPS-stimulated macrophages at 50 muM (P < 0.001); it significantly diminished inflammation-induced edema and COX-2, iNOS, and NF-kappaB protein levels were reduced compared to control group (P < 0.001). 3-o-methyl kaempferol tumor necrosis factor Mus musculus