Title : Phosphoproteome of signaling by ErbB2 in ovarian cancer cells.

Pub. Date : 2022 Apr 1

PMID : 35158093






2 Functional Relationships(s)
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1 To address this, we have undertaken a mass spectrometry approach to identify phosphoproteins specific for ErbB2 using the inhibitors Lapatinib and CP724714 in ovarian cancer cells. Lapatinib erb-b2 receptor tyrosine kinase 2 Homo sapiens
2 MARCKS was phosphorylated on stimulation of SKOV-3 cells with EGF that was inhibited by Lapatinib and CP724714 which was dependent on the kinase activity of ErbB2. Lapatinib erb-b2 receptor tyrosine kinase 2 Homo sapiens