Title : Copy number amplification of ENSA promotes the progression of triple-negative breast cancer via cholesterol biosynthesis.

Pub. Date : 2022 Feb 10

PMID : 35145111






4 Functional Relationships(s)
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Protein Name
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1 Mechanistically, we identify ENSA as an essential regulator of cholesterol biosynthesis in TNBC that upregulates the expression of sterol regulatory element-binding transcription factor 2 (SREBP2), a pivotal transcription factor in cholesterol biosynthesis. Cholesterol sterol regulatory element binding transcription factor 2 Homo sapiens
2 Mechanistically, we identify ENSA as an essential regulator of cholesterol biosynthesis in TNBC that upregulates the expression of sterol regulatory element-binding transcription factor 2 (SREBP2), a pivotal transcription factor in cholesterol biosynthesis. Cholesterol sterol regulatory element binding transcription factor 2 Homo sapiens
3 Mechanistically, we identify ENSA as an essential regulator of cholesterol biosynthesis in TNBC that upregulates the expression of sterol regulatory element-binding transcription factor 2 (SREBP2), a pivotal transcription factor in cholesterol biosynthesis. Cholesterol sterol regulatory element binding transcription factor 2 Homo sapiens
4 Mechanistically, we identify ENSA as an essential regulator of cholesterol biosynthesis in TNBC that upregulates the expression of sterol regulatory element-binding transcription factor 2 (SREBP2), a pivotal transcription factor in cholesterol biosynthesis. Cholesterol sterol regulatory element binding transcription factor 2 Homo sapiens