Title : Immune sensing of microbial metabolites: Action at the tumor.

Pub. Date : 2022 Feb 8

PMID : 35139348






1 Functional Relationships(s)
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1 (2022) reveal that metabolites of dietary tryptophan generated by the gut microbiota activate the aryl hydrocarbon receptor in myeloid cells, promoting an immune suppressive tumor microenvironment and facilitating pancreatic ductal adenocarcinoma growth. Tryptophan aryl hydrocarbon receptor Homo sapiens