Title : Identification of a promising hit from a new series of pyrazolo[1,5-a]pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro-apoptotic properties through a multistep in vitro assessment.

Pub. Date : 2022 Mar

PMID : 35134645






1 Functional Relationships(s)
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1 The molecular docking study revealed a unique binding mode at the ATP binding pocket of CDK1/Cyc B/Cks2 through its 2,4-dimethoxyphenyl-amino. Adenosine Triphosphate cyclin dependent kinase 1 Homo sapiens