Title : Targeted downregulation of HIF-1α for restraining circulating tumor microemboli mediated metastasis.

Pub. Date : 2022 Mar

PMID : 35124127






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 While knock-out of HIF-1alpha or therapeutically downregulating of HIF-1alpha via HIF-1alpha inhibitor (BAY87-2243)-loaded neutrophil cyto-pharmaceuticals (PNEs) could efficiently restrain CTM mediated lung metastasis. cyclohexane-1,2,4-tris(methylenesulfonate) hypoxia inducible factor 1 subunit alpha Homo sapiens
2 While knock-out of HIF-1alpha or therapeutically downregulating of HIF-1alpha via HIF-1alpha inhibitor (BAY87-2243)-loaded neutrophil cyto-pharmaceuticals (PNEs) could efficiently restrain CTM mediated lung metastasis. cyclohexane-1,2,4-tris(methylenesulfonate) hypoxia inducible factor 1 subunit alpha Homo sapiens
3 While knock-out of HIF-1alpha or therapeutically downregulating of HIF-1alpha via HIF-1alpha inhibitor (BAY87-2243)-loaded neutrophil cyto-pharmaceuticals (PNEs) could efficiently restrain CTM mediated lung metastasis. cyclohexane-1,2,4-tris(methylenesulfonate) hypoxia inducible factor 1 subunit alpha Homo sapiens
4 More importantly, we provide a promising strategy by targeted downregulation of HIF-1alpha in CTM via neutrophil cyto-pharmaceuticals for treatment of CTM mediated metastasis. cyclohexane-1,2,4-tris(methylenesulfonate) hypoxia inducible factor 1 subunit alpha Homo sapiens
5 More importantly, we provide a promising strategy by targeted downregulation of HIF-1alpha in CTM via neutrophil cyto-pharmaceuticals for treatment of CTM mediated metastasis. cyclohexane-1,2,4-tris(methylenesulfonate) hypoxia inducible factor 1 subunit alpha Homo sapiens