Title : Discovery of novel rigid analogs of 2-naphthol with potent anticancer activity through multi-target topoisomerase I & II and tyrosine kinase receptor EGFR & VEGFR-2 inhibition mechanism.

Pub. Date : 2022 Mar 1

PMID : 35123995






1 Functional Relationships(s)
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1 In addition, compounds 4a and 4b exhibited comparable inhibitory activity on tyrosine kinase receptors EGFR and VEGFR-2 kinases to that of the reference protein kinases inhibitor Sorafenib. Sorafenib kinase insert domain receptor Homo sapiens