Title : Magnesium promotes osteogenesis via increasing OPN expression and activating CaM/CaMKIV/CREB1 pathway.

Pub. Date : 2022 Jul

PMID : 35106922






4 Functional Relationships(s)
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1 Magnesium promotes osteogenesis via increasing OPN expression and activating CaM/CaMKIV/CREB1 pathway. Magnesium secreted phosphoprotein 1 Homo sapiens
2 Results showed that magnesium exerts a dose-dependent increase in the proliferation of MC3T3 and MG63 cells, and in the expression of osteopontin (OPN), a promising biomarker of osteogenesis. Magnesium secreted phosphoprotein 1 Homo sapiens
3 Results showed that magnesium exerts a dose-dependent increase in the proliferation of MC3T3 and MG63 cells, and in the expression of osteopontin (OPN), a promising biomarker of osteogenesis. Magnesium secreted phosphoprotein 1 Homo sapiens
4 These data indicated that the osteogenic effect of Mg is related to the activation OPN through CaM/CaMKIV/CREB1 signaling pathway. Magnesium secreted phosphoprotein 1 Homo sapiens