Title : miR-182 targeting reprograms tumor-associated macrophages and limits breast cancer progression.

Pub. Date : 2022 Feb 8

PMID : 35105806






1 Functional Relationships(s)
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1 Mechanistically, cancer cells induce miR-182 expression in macrophages by TGFbeta signaling, and miR-182 directly suppresses TLR4, leading to NFkappab inactivation and M2 polarization of TAMs. tams nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus