Title : Schisandrin B promotes Foxp3+ regulatory T cell expansion by activating heme oxygenase-1 in dendritic cells and exhibits immunomodulatory effects in Th2-mediated allergic asthma.

Pub. Date : 2022 Mar 5

PMID : 35085518






1 Functional Relationships(s)
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1 Herein, an in vitro study revealed that 20 muM of Sch B-treated bone-marrow-derived DCs exhibited a semi-mature phenotype that secreted low amounts of proinflammatory cytokines including interleukin (IL)-12, IL-1beta, IL-6, and tumor necrosis factor (TNF)-alpha, and expressed decreased levels of surface molecules of cluster of differentiation 80 (CD80) and CD86. schizandrin B interleukin 1 alpha Mus musculus