Title : Aurora Kinase A Is Involved in Controlling the Localization of Aquaporin-2 in Renal Principal Cells.

Pub. Date : 2022 Jan 11

PMID : 35054947






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The cAMP-dependent aquaporin-2 (AQP2) redistribution from intracellular vesicles into the plasma membrane of renal collecting duct principal cells induces water reabsorption and fine-tunes body water homeostasis. Cyclic AMP aquaporin 2 Rattus norvegicus
2 The AURKA-selective inhibitor Aurora-A inhibitor I and novel derivatives as well as a structurally different inhibitor, Alisertib, prevented the cAMP-induced redistribution of AQP2. Cyclic AMP aquaporin 2 Rattus norvegicus