| Protein Name | aquaporin 2 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25386 |
| Gene Symbol | Aqp2 |
| UniProt | P34080 (AQP2_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
198
Total Number of Articles : 345 |
Description |
aquaporin 2 |
| Gene Summary |
Enables PDZ domain binding activity; actin binding activity; and water transmembrane transporter activity. Involved in several processes, including actin filament depolymerization; cellular response to water deprivation; and response to glucagon. Located in several cellular components, including basolateral plasma membrane; cytoplasmic vesicle; and trans-Golgi network. Part of protein-containing complex. Used to study diabetes insipidus. Biomarker of hypertension and nephrogenic diabetes insipidus. Human ortholog(s) of this gene implicated in nephrogenic diabetes insipidus. Orthologous to human AQP2 (aquaporin 2). [provided by Alliance of Genome Resources, Apr 2022] |
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