Title : Indoleamine dioxygenase and tryptophan dioxygenase activities are regulated through GAPDH- and Hsp90-dependent control of their heme levels.

Pub. Date : 2022 Feb 20

PMID : 35051612






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Indoleamine dioxygenase and tryptophan dioxygenase activities are regulated through GAPDH- and Hsp90-dependent control of their heme levels. Heme glyceraldehyde-3-phosphate dehydrogenase Homo sapiens
2 We found that GAPDH delivered both mitochondrially-generated and exogenous heme to apo-IDO1 and apo-TDO in cells, potentially through a direct interaction with either enzyme. Heme glyceraldehyde-3-phosphate dehydrogenase Homo sapiens