Title : Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway.

Pub. Date : 2022 Feb 20

PMID : 35045311






2 Functional Relationships(s)
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1 Dietary iron overload also decreased mRNA and protein expression levels of glutathione peroxidase 4 (GPX4) and cystine-glutamate antiporter (SLC7A11), and increased mRNA and protein expression of acyl-CoA synthetase long-chain family member 4 (ACSL4), which are all markers of ferroptosis. Iron acyl-CoA synthetase long chain family member 4 Homo sapiens
2 Dietary iron overload also decreased mRNA and protein expression levels of glutathione peroxidase 4 (GPX4) and cystine-glutamate antiporter (SLC7A11), and increased mRNA and protein expression of acyl-CoA synthetase long-chain family member 4 (ACSL4), which are all markers of ferroptosis. Iron acyl-CoA synthetase long chain family member 4 Homo sapiens