Title : Preemptive pharmacogenetic testing to guide chemotherapy dosing in patients with gastrointestinal malignancies: a qualitative study of barriers to implementation.

Pub. Date : 2022 Jan 8

PMID : 34996412






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1 BACKGROUND: Pharmacogenetic (PGx) testing for germline variants in the DPYD and UGT1A1 genes can be used to guide fluoropyrimidine and irinotecan dosing, respectively. Irinotecan dihydropyrimidine dehydrogenase Homo sapiens