Pub. Date : 2022 Jan 7
PMID : 34993577
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tacrolimus induces remission in refractory and relapsing lupus nephritis by decreasing P-glycoprotein expression and function on peripheral blood lymphocytes. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Tacrolimus is a P-gp inhibitor and hence, may overcome this resistance. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | Expression and function of P-gp on PBL was measured by flow cytometry (as relative fluorescence index, RFI and Rhodamine dye efflux assay) before and 3 months after tacrolimus therapy. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | Tacrolimus achieves renal response in refractory/relapsing proliferative LN patients which may be partly related to overcoming P-glycoprotein mediated treatment unresponsiveness. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |