Pub. Date : 2022 May
PMID : 34981658
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Accumulations of secondary bile acids and oxysterols were found in both the serum and liver tissue of LXRalpha activated mice. | Oxysterols | nuclear receptor subfamily 1, group H, member 3 | Mus musculus |
| 2 | Conclusion: Our results indicated that chronic activation of LXRalpha promotes HCC, at least in part, by promoting innate immune suppressor as a result of accumulation of oxysterols, as well as up-regulation of the IL-6/Janus kinase/STAT3 signaling and complement pathways. | Oxysterols | nuclear receptor subfamily 1, group H, member 3 | Mus musculus |