Title : Discovery, X-ray structure and CPP-conjugation enabled uptake of p53/MDM2 macrocyclic peptide inhibitors.

Pub. Date : 2021 Dec 2

PMID : 34977581






1 Functional Relationships(s)
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1 X-Ray crystallography reveals a novel binding mode utilizing a unique pharmacophore to occupy the Phe/Trp/Leu pockets on MDM2. Leucine MDM2 proto-oncogene Homo sapiens