Pub. Date : 1987 Sep
PMID : 3497679
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of calcium ion concentration on the ability of fibrinogen and von Willebrand factor to support the ADP-induced aggregation of human platelets. | Adenosine Diphosphate | von Willebrand factor | Homo sapiens |
| 2 | In the low calcium medium, either vWf or fibrinogen supported biphasic aggregation in response to ADP, with thromboxane formation and release of granule contents. | Adenosine Diphosphate | von Willebrand factor | Homo sapiens |
| 3 | Although vWf supports ADP-induced aggregation when the concentration of ionized calcium is in the micromolar range, it does not support ADP-induced aggregation in the presence of a concentration of ionized calcium in the physiological range, indicating that vWf probably cannot substitute for fibrinogen in supporting ADP-induced aggregation in vivo. | Adenosine Diphosphate | von Willebrand factor | Homo sapiens |