Pub. Date : 2022 Mar
PMID : 34968641
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ovatodiolide protects ischemia-reperfusion-induced neuronal injury via microglial neuroinflammation via mediating SIRT1/NF-kappaB pathway. | ovatodiolide | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 2 | OVA mitigated NF-kappaB phosphorylation in BV2 cells, whereas boosted SIRT1 expression. | ovatodiolide | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 3 | Additionally, OVA inactivated the NF-kappaB pathway and up-regulated SIRT1 in the I/R rat model. | ovatodiolide | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 4 | CONCLUSION: OVA prevented rats from brain I/R damage by hampering neuronal apoptosis and microglial inflammation via the SIRT1-NF-kappaB pathway. | ovatodiolide | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |