Title : Exploring the inclusion interaction of estradiol with β-CD and HP-β-CD with the help of molecular dynamics simulation as well as multi-spectroscopic approaches.

Pub. Date : 2022 Mar 15

PMID : 34954480






6 Functional Relationships(s)
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1 The findings revealed that estradiol enclosed into the cavity of beta-CD and HP-beta-CD and produced the estradiol-beta-CD and estradiol-HP-beta-CD complexes with the stoichiometry of 1:1. 2-Hydroxypropyl-beta-cyclodextrin ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens
2 The findings revealed that estradiol enclosed into the cavity of beta-CD and HP-beta-CD and produced the estradiol-beta-CD and estradiol-HP-beta-CD complexes with the stoichiometry of 1:1. 2-Hydroxypropyl-beta-cyclodextrin ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens
3 The findings revealed that estradiol enclosed into the cavity of beta-CD and HP-beta-CD and produced the estradiol-beta-CD and estradiol-HP-beta-CD complexes with the stoichiometry of 1:1. 2-Hydroxypropyl-beta-cyclodextrin ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens
4 Moreover, it was confirmed from the results of molecular modeling that estradiol inserted into the hydrophobic cavity of beta-CD and HP-beta-CD and form a stable estradiol-CD complexes. 2-Hydroxypropyl-beta-cyclodextrin ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens
5 And, it is also observed that the phenyl moiety in estradiol is almost parallel to the central axis of beta-CD and HP-beta-CD, and the phenyl moiety was located on wider rim of beta-CD and HP-beta-CD. 2-Hydroxypropyl-beta-cyclodextrin ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens
6 And, it is also observed that the phenyl moiety in estradiol is almost parallel to the central axis of beta-CD and HP-beta-CD, and the phenyl moiety was located on wider rim of beta-CD and HP-beta-CD. 2-Hydroxypropyl-beta-cyclodextrin ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens