Title : Integrating network pharmacology deciphers the action mechanism of Zuojin capsule in suppressing colorectal cancer.

Pub. Date : 2022 Feb

PMID : 34942456






1 Functional Relationships(s)
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1 CONCLUSIONS: In summary, combined network pharmacology and biological experiments proved that the main ingredients of ZJC such as quercetin, (R)-Canadine, palmatine, rutaecarpine, evodiamine, beta-sitosterol and berberine can target CDKN1A, Bcl2, E2F1, PRKCB, MYC, CDK2 and MMP9 to combat colorectal cancer. Quercetin cyclin dependent kinase 2 Homo sapiens