Pub. Date : 2022 Jan 12
PMID : 34931793
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Herein, multidrug resistance protein 1 (MDR1) siRNA is used as the skeleton to assemble chemotherapeutic cisplatin (CDDP) and divalent copper ion (Cu2+) for constructing a carrier-free Cu-siMDR-CDDP system. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Herein, multidrug resistance protein 1 (MDR1) siRNA is used as the skeleton to assemble chemotherapeutic cisplatin (CDDP) and divalent copper ion (Cu2+) for constructing a carrier-free Cu-siMDR-CDDP system. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | Herein, multidrug resistance protein 1 (MDR1) siRNA is used as the skeleton to assemble chemotherapeutic cisplatin (CDDP) and divalent copper ion (Cu2+) for constructing a carrier-free Cu-siMDR-CDDP system. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | Herein, multidrug resistance protein 1 (MDR1) siRNA is used as the skeleton to assemble chemotherapeutic cisplatin (CDDP) and divalent copper ion (Cu2+) for constructing a carrier-free Cu-siMDR-CDDP system. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 5 | Besides, delivery of MDR1 siRNA is facilitated by HO -triggered lysosome destruction, thus inhibiting P-glycoprotein (P-gp) expression and CDDP efflux. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |