Title : Autophagy of Spinal Microglia Affects the Activation of Microglia through the PI3K/AKT/mTOR Signaling Pathway.

Pub. Date : 2022 Feb 1

PMID : 34902496






1 Functional Relationships(s)
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1 In both in vivo ISCI model in rats and in vitro OGD model in BV-2 cells, the PI3K/AKT/mTOR pathway showed to be inhibited, whereas the PI3K/AKT/mTOR pathway was further inhibited by mild hypothermia in ISCI rats or rapamycin treatment in OGD-stimulated BV-2 cells. Sirolimus mechanistic target of rapamycin kinase Mus musculus