PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34886886-11 2021 CONCLUSION: Evidence indicated that the endogenous p53 status affected the sensitivity of ATC cells to EVO-induced apoptosis and G2/M arrest, revealing the potential role of p53 related to increased ROS production and disrupted MMP in the anticancer actions of EVO, and alkylation at position 14 of EVO is a critical substitution for apoptosis of ATC cells. Reactive Oxygen Species 199-202 tumor protein p53 Homo sapiens 51-54 34886886-11 2021 CONCLUSION: Evidence indicated that the endogenous p53 status affected the sensitivity of ATC cells to EVO-induced apoptosis and G2/M arrest, revealing the potential role of p53 related to increased ROS production and disrupted MMP in the anticancer actions of EVO, and alkylation at position 14 of EVO is a critical substitution for apoptosis of ATC cells. Reactive Oxygen Species 199-202 tumor protein p53 Homo sapiens 174-177