Pub. Date : 2021 Nov 30
PMID : 34885145
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DNA methylation (5-methylcytosine, 5mC) was once viewed as a stable epigenetic modification until Rao and colleagues identified Ten-eleven translocation 1 (TET1) as the first 5mC dioxygenase in 2009. | 5-Methylcytidine 5'-monophosphate | tet methylcytosine dioxygenase 1 | Homo sapiens |
| 2 | DNA methylation (5-methylcytosine, 5mC) was once viewed as a stable epigenetic modification until Rao and colleagues identified Ten-eleven translocation 1 (TET1) as the first 5mC dioxygenase in 2009. | 5-Methylcytidine 5'-monophosphate | tet methylcytosine dioxygenase 1 | Homo sapiens |
| 3 | TET family genes (including TET1, TET2, and TET3) encode proteins that can catalyze 5mC oxidation and consequently modulate DNA methylation, not only regulating embryonic development and cellular differentiation, but also playing critical roles in various physiological and pathophysiological processes. | 5-Methylcytidine 5'-monophosphate | tet methylcytosine dioxygenase 1 | Homo sapiens |