Title : Cytotoxic Aβ Protofilaments Are Generated in the Process of Aβ Fibril Disaggregation.

Pub. Date : 2021 Nov 26

PMID : 34884584






3 Functional Relationships(s)
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Protein Name
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1 Abeta fibrils were reported to be disaggregated by treatment with small compounds, such as epigallocatechin gallate (EGCG) and dopamine (DA), and a loss of fibril shape and decrease in cytotoxicity were observed. epigallocatechin gallate amyloid beta precursor protein Homo sapiens
2 Abeta fibrils were reported to be disaggregated by treatment with small compounds, such as epigallocatechin gallate (EGCG) and dopamine (DA), and a loss of fibril shape and decrease in cytotoxicity were observed. epigallocatechin gallate amyloid beta precursor protein Homo sapiens
3 A cytotoxicity assay revealed that Abeta fibrils incubated with a low concentration of EGCG and DA showed higher cytotoxicity than Abeta fibrils alone. epigallocatechin gallate amyloid beta precursor protein Homo sapiens