Title : Human fetal membrane IL-1β production in response to bacterial components is mediated by uric-acid induced NLRP3 inflammasome activation.

Pub. Date : 2022 Feb

PMID : 34875574






1 Functional Relationships(s)
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1 LPS, PGN, and MDP induced FM IL-1beta and IL-18 secretion in a non-pyroptotic manner through activation of the NLRP3 inflammasome with contributions from ATP release through Pannexin-1, and ROS signaling. Adenosine Triphosphate interleukin 18 Homo sapiens