Title : Resveratrol enhanced chemosensitivity by reversing macrophage polarization in breast cancer.

Pub. Date : 2022 May

PMID : 34859370






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 RESULTS: Our results demonstrated that resveratrol significantly reduced cell proliferation and enhanced chemosensitivity in breast cancer cells by inhibiting production of IL-6 and STAT3 activation. Resveratrol interleukin 6 Homo sapiens
2 Further, resveratrol decreased IL-6 levels in LPS-treated differentiated macrophages. Resveratrol interleukin 6 Homo sapiens
3 CONCLUSION: This study revealed that resveratrol inhibited breast cancer cell proliferation by promoting M1/M2 macrophage polarization ratio and suppressing IL-6/pSTAT3 pathway. Resveratrol interleukin 6 Homo sapiens